diff --git a/Lib/test/test_typing.py b/Lib/test/test_typing.py
index c6f08ff8a052ab..a2b76ed1303a33 100644
--- a/Lib/test/test_typing.py
+++ b/Lib/test/test_typing.py
@@ -6837,6 +6837,24 @@ def test_get_type_hints_wrapped_decoratored_func(self):
         self.assertEqual(gth(ForRefExample.func), expects)
         self.assertEqual(gth(ForRefExample.nested), expects)
 
+    def test_get_type_hints_wrapped_cycle_self(self):
+        # gh-146553: __wrapped__ self-reference must raise ValueError,
+        # not loop forever.
+        def f(x: int) -> str: ...
+        f.__wrapped__ = f
+        with self.assertRaisesRegex(ValueError, 'wrapper loop'):
+            get_type_hints(f)
+
+    def test_get_type_hints_wrapped_cycle_mutual(self):
+        # gh-146553: mutual __wrapped__ cycle (a -> b -> a) must raise
+        # ValueError, not loop forever.
+        def a(): ...
+        def b(): ...
+        a.__wrapped__ = b
+        b.__wrapped__ = a
+        with self.assertRaisesRegex(ValueError, 'wrapper loop'):
+            get_type_hints(a)
+
     def test_get_type_hints_annotated(self):
         def foobar(x: List['X']): ...
         X = Annotated[int, (1, 10)]
diff --git a/Lib/typing.py b/Lib/typing.py
index e78fb8b71a996c..7e97e89e4ed1de 100644
--- a/Lib/typing.py
+++ b/Lib/typing.py
@@ -172,6 +172,16 @@ def __getattr__(self, attr):
 _lazy_annotationlib = _LazyAnnotationLib()
 
 
+class _LazyInspect:
+    def __getattr__(self, attr):
+        global _lazy_inspect
+        import inspect
+        _lazy_inspect = inspect
+        return getattr(inspect, attr)
+
+_lazy_inspect = _LazyInspect()
+
+
 def _type_convert(arg, module=None, *, allow_special_forms=False, owner=None):
     """For converting None to type(None), and strings to ForwardRef."""
     if arg is None:
@@ -1962,16 +1972,6 @@ def _allow_reckless_class_checks(depth=2):
 }
 
 
-@functools.cache
-def _lazy_load_getattr_static():
-    # Import getattr_static lazily so as not to slow down the import of typing.py
-    # Cache the result so we don't slow down _ProtocolMeta.__instancecheck__ unnecessarily
-    from inspect import getattr_static
-    return getattr_static
-
-
-_cleanups.append(_lazy_load_getattr_static.cache_clear)
-
 def _pickle_psargs(psargs):
     return ParamSpecArgs, (psargs.__origin__,)
 
@@ -2104,7 +2104,7 @@ def __instancecheck__(cls, instance):
         if _abc_instancecheck(cls, instance):
             return True
 
-        getattr_static = _lazy_load_getattr_static()
+        getattr_static = _lazy_inspect.getattr_static
         for attr in cls.__protocol_attrs__:
             try:
                 val = getattr_static(instance, attr)
@@ -2483,10 +2483,8 @@ def get_type_hints(obj, globalns=None, localns=None, include_extras=False,
         if isinstance(obj, types.ModuleType):
             globalns = obj.__dict__
         else:
-            nsobj = obj
             # Find globalns for the unwrapped object.
-            while hasattr(nsobj, '__wrapped__'):
-                nsobj = nsobj.__wrapped__
+            nsobj = _lazy_inspect.unwrap(obj)
             globalns = getattr(nsobj, '__globals__', {})
         if localns is None:
             localns = globalns
diff --git a/Misc/NEWS.d/next/Library/2026-03-28-11-43-25.gh-issue-146553.mXaWza.rst b/Misc/NEWS.d/next/Library/2026-03-28-11-43-25.gh-issue-146553.mXaWza.rst
new file mode 100644
index 00000000000000..b75cdc14725a0c
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2026-03-28-11-43-25.gh-issue-146553.mXaWza.rst
@@ -0,0 +1,4 @@
+Fix :func:`typing.get_type_hints` hanging indefinitely when a callable has a
+circular ``__wrapped__`` chain (e.g. ``f.__wrapped__ = f``). A
+:exc:`ValueError` is now raised on cycle detection, matching the behavior of
+:func:`inspect.unwrap`.