diff --git a/packages/react-native/Libraries/StyleSheet/StyleSheetTypes.d.ts b/packages/react-native/Libraries/StyleSheet/StyleSheetTypes.d.ts
index c951a773d0ec..ef72aab6b704 100644
--- a/packages/react-native/Libraries/StyleSheet/StyleSheetTypes.d.ts
+++ b/packages/react-native/Libraries/StyleSheet/StyleSheetTypes.d.ts
@@ -568,7 +568,8 @@ export type FontVariant =
   | 'stylistic-seventeen'
   | 'stylistic-eighteen'
   | 'stylistic-nineteen'
-  | 'stylistic-twenty';
+  | 'stylistic-twenty'
+  | 'case-sensitive';
 export interface TextStyleIOS extends ViewStyle {
   fontVariant?: FontVariant[] | undefined;
   textDecorationColor?: ColorValue | undefined;
diff --git a/packages/react-native/Libraries/StyleSheet/StyleSheetTypes.js b/packages/react-native/Libraries/StyleSheet/StyleSheetTypes.js
index 1bf46c32b078..e7714f394a7b 100644
--- a/packages/react-native/Libraries/StyleSheet/StyleSheetTypes.js
+++ b/packages/react-native/Libraries/StyleSheet/StyleSheetTypes.js
@@ -990,7 +990,8 @@ export type ____FontVariant_Internal =
   | 'stylistic-seventeen'
   | 'stylistic-eighteen'
   | 'stylistic-nineteen'
-  | 'stylistic-twenty';
+  | 'stylistic-twenty'
+  | 'case-sensitive';
 
 export type ____FontVariantArray_Internal =
   ReadonlyArray<____FontVariant_Internal>;
diff --git a/packages/react-native/Libraries/StyleSheet/__tests__/processFontVariant-test.js b/packages/react-native/Libraries/StyleSheet/__tests__/processFontVariant-test.js
index 0c93e06a9217..72bec7c64c2c 100644
--- a/packages/react-native/Libraries/StyleSheet/__tests__/processFontVariant-test.js
+++ b/packages/react-native/Libraries/StyleSheet/__tests__/processFontVariant-test.js
@@ -28,6 +28,15 @@ describe('processFontVariant', () => {
     expect(processFontVariant('   tabular-nums')).toEqual(['tabular-nums']);
   });
 
+  it('should accept case-sensitive variant', () => {
+    expect(processFontVariant(['case-sensitive'])).toEqual(['case-sensitive']);
+    expect(processFontVariant('case-sensitive')).toEqual(['case-sensitive']);
+    expect(processFontVariant(['case-sensitive', 'tabular-nums'])).toEqual([
+      'case-sensitive',
+      'tabular-nums',
+    ]);
+  });
+
   it('should accept string with multiple values', () => {
     expect(processFontVariant('oldstyle-nums lining-nums')).toEqual([
       'oldstyle-nums',
diff --git a/packages/react-native/React/Views/RCTFont.mm b/packages/react-native/React/Views/RCTFont.mm
index 675f40c3131c..ce34198f9203 100644
--- a/packages/react-native/React/Views/RCTFont.mm
+++ b/packages/react-native/React/Views/RCTFont.mm
@@ -365,7 +365,11 @@ + (RCTFontVariantDescriptor *)RCTFontVariantDescriptor:(id)json
       @"stylistic-twenty" : @{
         UIFontFeatureTypeIdentifierKey : @(kStylisticAlternativesType),
         UIFontFeatureSelectorIdentifierKey : @(kStylisticAltTwentyOnSelector),
-      }
+      },
+      @"case-sensitive" : @{
+        UIFontFeatureTypeIdentifierKey : @(kCaseSensitiveLayoutType),
+        UIFontFeatureSelectorIdentifierKey : @(kCaseSensitiveLayoutOnSelector),
+      },
     };
   });
   RCTFontVariantDescriptor *value = mapping[json];
diff --git a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/views/text/ReactTypefaceUtils.kt b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/views/text/ReactTypefaceUtils.kt
index e33daa691f31..a06d7f57f73f 100644
--- a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/views/text/ReactTypefaceUtils.kt
+++ b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/views/text/ReactTypefaceUtils.kt
@@ -90,6 +90,7 @@ public object ReactTypefaceUtils {
         "stylistic-eighteen" -> features.add("'ss18'")
         "stylistic-nineteen" -> features.add("'ss19'")
         "stylistic-twenty" -> features.add("'ss20'")
+        "case-sensitive" -> features.add("'case'")
       }
     }
     return features.joinToString(", ")
diff --git a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/views/text/TextAttributeProps.kt b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/views/text/TextAttributeProps.kt
index 45c8bec4c2b8..c9543746326f 100644
--- a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/views/text/TextAttributeProps.kt
+++ b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/views/text/TextAttributeProps.kt
@@ -234,6 +234,7 @@ public class TextAttributeProps private constructor() {
           "stylistic-eighteen" -> features.add("'ss18'")
           "stylistic-nineteen" -> features.add("'ss19'")
           "stylistic-twenty" -> features.add("'ss20'")
+          "case-sensitive" -> features.add("'case'")
         }
       }
     }
diff --git a/packages/react-native/ReactCommon/react/renderer/attributedstring/conversions.h b/packages/react-native/ReactCommon/react/renderer/attributedstring/conversions.h
index 331e2019338a..06eba877e4f7 100644
--- a/packages/react-native/ReactCommon/react/renderer/attributedstring/conversions.h
+++ b/packages/react-native/ReactCommon/react/renderer/attributedstring/conversions.h
@@ -372,6 +372,8 @@ inline std::optional<FontVariant> fontVariantFromCSSFontVariant(CSSFontVariant c
       return FontVariant::StylisticNineteen;
     case CSSFontVariant::StylisticTwenty:
       return FontVariant::StylisticTwenty;
+    case CSSFontVariant::CaseSensitive:
+      return FontVariant::CaseSensitive;
     case CSSFontVariant::CommonLigatures:
     case CSSFontVariant::NoCommonLigatures:
     case CSSFontVariant::DiscretionaryLigatures:
@@ -442,6 +444,8 @@ parseProcessedFontVariant(const PropsParserContext & /*context*/, const RawValue
         result = (FontVariant)((int)result | (int)FontVariant::StylisticNineteen);
       } else if (item == "stylistic-twenty") {
         result = (FontVariant)((int)result | (int)FontVariant::StylisticTwenty);
+      } else if (item == "case-sensitive") {
+        result = (FontVariant)((int)result | (int)FontVariant::CaseSensitive);
       } else {
         LOG(ERROR) << "Unsupported FontVariant value: " << item;
       }
@@ -564,6 +568,9 @@ inline std::string toString(const FontVariant &fontVariant)
   if (((int)fontVariant & (int)FontVariant::StylisticTwenty) != 0) {
     result += "stylistic-twenty" + separator;
   }
+  if (((int)fontVariant & (int)FontVariant::CaseSensitive) != 0) {
+    result += "case-sensitive" + separator;
+  }
 
   if (!result.empty()) {
     result.erase(result.length() - separator.length());
@@ -1237,6 +1244,9 @@ inline MapBuffer toMapBuffer(const FontVariant &fontVariant)
   if ((int)fontVariant & (int)FontVariant::StylisticTwenty) {
     builder.putString(index++, "stylistic-twenty");
   }
+  if ((int)fontVariant & (int)FontVariant::CaseSensitive) {
+    builder.putString(index++, "case-sensitive");
+  }
 
   return builder.build();
 }
diff --git a/packages/react-native/ReactCommon/react/renderer/attributedstring/primitives.h b/packages/react-native/ReactCommon/react/renderer/attributedstring/primitives.h
index d23104518c74..eab5ff714266 100644
--- a/packages/react-native/ReactCommon/react/renderer/attributedstring/primitives.h
+++ b/packages/react-native/ReactCommon/react/renderer/attributedstring/primitives.h
@@ -62,7 +62,8 @@ enum class FontVariant : int {
   StylisticSeventeen = 1 << 22,
   StylisticEighteen = 1 << 23,
   StylisticNineteen = 1 << 24,
-  StylisticTwenty = 1 << 25
+  StylisticTwenty = 1 << 25,
+  CaseSensitive = 1 << 26
 };
 
 enum class DynamicTypeRamp {
@@ -132,7 +133,12 @@ enum class LineBreakMode {
   Tail // Truncate at tail of line: "abcd..."
 };
 
-enum class TextDecorationLineType { None, Underline, Strikethrough, UnderlineStrikethrough };
+enum class TextDecorationLineType {
+  None,
+  Underline,
+  Strikethrough,
+  UnderlineStrikethrough
+};
 
 enum class TextDecorationStyle { Solid, Double, Dotted, Dashed };
 
diff --git a/packages/react-native/ReactCommon/react/renderer/css/CSSFontVariant.h b/packages/react-native/ReactCommon/react/renderer/css/CSSFontVariant.h
index b4749170fe43..6f9db1f48687 100644
--- a/packages/react-native/ReactCommon/react/renderer/css/CSSFontVariant.h
+++ b/packages/react-native/ReactCommon/react/renderer/css/CSSFontVariant.h
@@ -26,7 +26,8 @@ enum class CSSFontVariant : std::underlying_type_t<CSSKeyword> {
   CommonLigatures = to_underlying(CSSKeyword::CommonLigatures),
   NoCommonLigatures = to_underlying(CSSKeyword::NoCommonLigatures),
   DiscretionaryLigatures = to_underlying(CSSKeyword::DiscretionaryLigatures),
-  NoDiscretionaryLigatures = to_underlying(CSSKeyword::NoDiscretionaryLigatures),
+  NoDiscretionaryLigatures =
+      to_underlying(CSSKeyword::NoDiscretionaryLigatures),
   HistoricalLigatures = to_underlying(CSSKeyword::HistoricalLigatures),
   NoHistoricalLigatures = to_underlying(CSSKeyword::NoHistoricalLigatures),
   Contextual = to_underlying(CSSKeyword::Contextual),
@@ -52,6 +53,7 @@ enum class CSSFontVariant : std::underlying_type_t<CSSKeyword> {
   StylisticEighteen = to_underlying(CSSKeyword::StylisticEighteen),
   StylisticNineteen = to_underlying(CSSKeyword::StylisticNineteen),
   StylisticTwenty = to_underlying(CSSKeyword::StylisticTwenty),
+  CaseSensitive = to_underlying(CSSKeyword::CaseSensitive),
 };
 
 static_assert(CSSDataType<CSSFontVariant>);
diff --git a/packages/react-native/ReactCommon/react/renderer/css/CSSKeyword.h b/packages/react-native/ReactCommon/react/renderer/css/CSSKeyword.h
index f75901853c86..2b132929e1d9 100644
--- a/packages/react-native/ReactCommon/react/renderer/css/CSSKeyword.h
+++ b/packages/react-native/ReactCommon/react/renderer/css/CSSKeyword.h
@@ -28,6 +28,7 @@ enum class CSSKeyword : uint8_t {
   Baseline,
   Block,
   Bottom,
+  CaseSensitive,
   Center,
   Clip,
   Column,
@@ -150,6 +151,7 @@ CSS_DEFINE_KEYWORD(Auto, "auto")
 CSS_DEFINE_KEYWORD(Baseline, "baseline")
 CSS_DEFINE_KEYWORD(Block, "block")
 CSS_DEFINE_KEYWORD(Bottom, "bottom")
+CSS_DEFINE_KEYWORD(CaseSensitive, "case-sensitive")
 CSS_DEFINE_KEYWORD(Center, "center")
 CSS_DEFINE_KEYWORD(Clip, "clip")
 CSS_DEFINE_KEYWORD(Column, "column")
@@ -263,6 +265,7 @@ constexpr std::optional<KeywordT> parseCSSKeyword(std::string_view ident)
     CSS_HANDLE_KEYWORD(Baseline)
     CSS_HANDLE_KEYWORD(Block)
     CSS_HANDLE_KEYWORD(Bottom)
+    CSS_HANDLE_KEYWORD(CaseSensitive)
     CSS_HANDLE_KEYWORD(Center)
     CSS_HANDLE_KEYWORD(Clip)
     CSS_HANDLE_KEYWORD(Column)
@@ -361,7 +364,8 @@ constexpr std::optional<KeywordT> parseCSSKeyword(std::string_view ident)
 
 template <CSSKeywordSet KeywordT>
 struct CSSDataTypeParser<KeywordT> {
-  static constexpr auto consumePreservedToken(const CSSPreservedToken &token) -> std::optional<KeywordT>
+  static constexpr auto consumePreservedToken(const CSSPreservedToken &token)
+      -> std::optional<KeywordT>
   {
     if (token.type() == CSSTokenType::Ident) {
       return parseCSSKeyword<KeywordT>(token.stringValue());
diff --git a/packages/react-native/ReactCommon/react/renderer/textlayoutmanager/platform/ios/react/renderer/textlayoutmanager/RCTFontProperties.h b/packages/react-native/ReactCommon/react/renderer/textlayoutmanager/platform/ios/react/renderer/textlayoutmanager/RCTFontProperties.h
index efbfdf0d894e..9466627af681 100644
--- a/packages/react-native/ReactCommon/react/renderer/textlayoutmanager/platform/ios/react/renderer/textlayoutmanager/RCTFontProperties.h
+++ b/packages/react-native/ReactCommon/react/renderer/textlayoutmanager/platform/ios/react/renderer/textlayoutmanager/RCTFontProperties.h
@@ -44,6 +44,7 @@ typedef NS_OPTIONS(NSInteger, RCTFontVariant) {
   RCTFontVariantStylisticEighteen = 1 << 23,
   RCTFontVariantStylisticNineteen = 1 << 24,
   RCTFontVariantStylisticTwenty = 1 << 25,
+  RCTFontVariantCaseSensitive = 1 << 26,
 };
 
 struct RCTFontProperties {
diff --git a/packages/react-native/ReactCommon/react/renderer/textlayoutmanager/platform/ios/react/renderer/textlayoutmanager/RCTFontUtils.mm b/packages/react-native/ReactCommon/react/renderer/textlayoutmanager/platform/ios/react/renderer/textlayoutmanager/RCTFontUtils.mm
index 9b04cadc22f5..2cc0b8234540 100644
--- a/packages/react-native/ReactCommon/react/renderer/textlayoutmanager/platform/ios/react/renderer/textlayoutmanager/RCTFontUtils.mm
+++ b/packages/react-native/ReactCommon/react/renderer/textlayoutmanager/platform/ios/react/renderer/textlayoutmanager/RCTFontUtils.mm
@@ -166,6 +166,10 @@ static RCTFontStyle RCTGetFontStyle(UIFont *font)
            UIFontFeatureTypeIdentifierKey : @(kStylisticAlternativesType),
            UIFontFeatureSelectorIdentifierKey : @(kStylisticAltTwentyOnSelector),
          }},
+        {RCTFontVariantCaseSensitive, @{
+           UIFontFeatureTypeIdentifierKey : @(kCaseSensitiveLayoutType),
+           UIFontFeatureSelectorIdentifierKey : @(kCaseSensitiveLayoutOnSelector),
+         }},
     };
   });
 
@@ -244,6 +248,9 @@ static RCTFontStyle RCTGetFontStyle(UIFont *font)
   if ((fontVariant & RCTFontVariantStylisticTwenty) != 0) {
     [fontFeatures addObject:mapping[RCTFontVariantStylisticTwenty]];
   }
+  if ((fontVariant & RCTFontVariantCaseSensitive) != 0) {
+    [fontFeatures addObject:mapping[RCTFontVariantCaseSensitive]];
+  }
 
   return fontFeatures;
 }
diff --git a/packages/react-native/ReactNativeApi.d.ts b/packages/react-native/ReactNativeApi.d.ts
index 261ef45f8c2f..60741264e10c 100644
--- a/packages/react-native/ReactNativeApi.d.ts
+++ b/packages/react-native/ReactNativeApi.d.ts
@@ -4,7 +4,7 @@
  * This source code is licensed under the MIT license found in the
  * LICENSE file in the root directory of this source tree.
  *
- * @generated SignedSource<<d6790c241d1bd46a735efba34eeb4742>>
+ * @generated SignedSource<<ef724dd0afd6cc872cf4bfe8443dbf36>>
  *
  * This file was generated by scripts/js-api/build-types/index.js.
  */
@@ -628,6 +628,7 @@ declare type ____FlattenStyleProp_Internal<
     ? any
     : ____FlattenStyleProp_Helper<TStyleProp>
 declare type ____FontVariant_Internal =
+  | "case-sensitive"
   | "common-ligatures"
   | "contextual"
   | "discretionary-ligatures"
@@ -6067,7 +6068,7 @@ export {
   AlertOptions, // a0cdac0f
   AlertType, // 5ab91217
   AndroidKeyboardEvent, // e03becc8
-  Animated, // 0652b5d1
+  Animated, // 91b43ef7
   AppConfig, // ce4209a7
   AppRegistry, // 5edf0524
   AppState, // 12012be5
@@ -6117,7 +6118,7 @@ export {
   FlatList, // 8c50f04a
   FlatListProps, // e170f2c9
   FocusEvent, // 62fc1eb8
-  FontVariant, // 7c7558bb
+  FontVariant, // 8779dc78
   GestureResponderEvent, // f693e9a5
   GestureResponderHandlers, // cc70e4cb
   Handle, // 2d65285d
@@ -6278,7 +6279,7 @@ export {
   StatusBarProps, // 06c98add
   StatusBarStyle, // 986b2051
   StyleProp, // fa0e9b4a
-  StyleSheet, // e77dd046
+  StyleSheet, // 614889ca
   SubmitBehavior, // c4ddf490
   Switch, // 3434138b
   SwitchChangeEvent, // 63e9c50b
@@ -6287,9 +6288,9 @@ export {
   TVViewPropsIOS, // 330ce7b5
   TargetedEvent, // 16e98910
   TaskProvider, // 266dedf2
-  Text, // 717d25fe
+  Text, // 044dd5f4
   TextContentType, // 239b3ecc
-  TextInput, // ed3a8375
+  TextInput, // 68d39b8a
   TextInputAndroidProps, // 3f09ce49
   TextInputChangeEvent, // 3ab11bb4
   TextInputContentSizeChangeEvent, // f71f8571
@@ -6297,12 +6298,12 @@ export {
   TextInputFocusEvent, // 020507e6
   TextInputIOSProps, // 0d05a855
   TextInputKeyPressEvent, // 3924ad9b
-  TextInputProps, // 9b370db2
+  TextInputProps, // 0f04d5b7
   TextInputSelectionChangeEvent, // d4d10630
   TextInputSubmitEditingEvent, // 22885c31
   TextLayoutEvent, // 73ab173e
-  TextProps, // 68a1c0e8
-  TextStyle, // bb9b7a58
+  TextProps, // f62cde6d
+  TextStyle, // b327f541
   ToastAndroid, // 88a8969a
   Touchable, // da3239ee
   TouchableHighlight, // 9d67503a
diff --git a/packages/rn-tester/js/examples/Text/TextExample.ios.js b/packages/rn-tester/js/examples/Text/TextExample.ios.js
index 68b4a103a87e..7a92312ec99d 100644
--- a/packages/rn-tester/js/examples/Text/TextExample.ios.js
+++ b/packages/rn-tester/js/examples/Text/TextExample.ios.js
@@ -1329,6 +1329,21 @@ const examples = [
             1111{'\n'}
             2222{'\n'}
           </Text>
+          <Text style={{fontFamily: 'KefaIII-Regular', fontSize: 28}}>
+            (E-H) [E-H]+ Case sensitive (OFF)
+          </Text>
+          <Text
+            style={{
+              fontFamily: 'KefaIII-Regular',
+              fontSize: 28,
+              fontVariant: ['case-sensitive'],
+            }}>
+            (E-H) [E-H]+ Case sensitive (ON)
+          </Text>
+          <Text style={{color: 'gray', fontSize: 12}}>
+            Note: the visual rendering differences for this font are only
+            discernible on-device, not in a simulator.
+          </Text>
         </View>
       );
     },